Ka hoʻomaopopo ʻana i ka Narrowband UVB Phototherapy

Narrowband UVB Phototherapy – Nā Kumu

He mea paʻakikī ka hoʻomaopopo ʻana i ka UVB-Narrowband akā e hana mākou i ka maikaʻi loa.

Ua lilo ʻo "Narrowband" UVB i ka phototherapy t no ka mea hāʻawi ʻo ia i nā huina nui loa o nā lōʻihi hawewe maikaʻi loa o ke kukui UV, ʻoiai e hōʻemi ana i nā lōʻihi hawewe hiki ke pōʻino.

ʻike mau “Broadband” Hoʻopuka nā kukui UVB i ka mālamalama ma kahi ākea ma luna o ka spectrum UVB, me nā lōʻihi hawewe lapaʻau e pili ana i ka mālama ʻana i nā maʻi ʻili, a me nā lōʻihi hawewe pōkole e pili ana i ka puhi ʻana i ka lā (erythema). He pōmaikaʻi maikaʻi ʻole ka Sunburning, hoʻonui i ka pilikia o ka maʻi maʻi ʻili, hōʻeha i ka mea maʻi, a kaupalena i ka nui o ka UVB therapeutic hiki ke lawe.

“Narrowband” ʻO nā kukui UVB, ma ka ʻaoʻao ʻē aʻe, e hoʻokuʻu i ka mālamalama ma luna o kahi pōkole loa o nā nalu nalu i hoʻopaʻa ʻia i ka pae therapeutic a me ka liʻiliʻi loa i ka laulā o ka lā, e hoʻohana ana i kahi "wahi momona" ma waena o nā mea ʻelua a puni 311 nm. No laila, ʻoi aku ka palekana a ʻoi aku ka maikaʻi o ka UVB-Narrowband ma mua o ka UVB-Broadband, akā koi ʻia nā manawa lapaʻau lōʻihi a i ʻole nā ​​​​mea hana me nā ʻōpuʻu hou aʻe e loaʻa ai ka nui o ka nui, aia ma ka hoʻomaka ʻana o ka ʻulaʻula o ka ʻili ma hope o ka mālama ʻana, i kapa ʻia ʻo "sub-erythema". . Loaʻa i nā hiʻohiʻona UVB-Narrowband o Solarc kahi suffix "UVB-NB" ma ka helu kumu hoʻohālike, e like me 1780UVB‑NB. ʻO nā hiʻohiʻona UVB-Broadband o Solarc he suffix "UVB" wale nō, e like me 1740UVB. Ua hoʻomohala ʻia ʻo "Narrowband UVB" e Philips Lighting of Holland a ʻike ʻia hoʻi ʻo: Narrow Band UVB, UVB Narrowband, UVB‑NB, NB‑UVB, TL/01, TL‑01, TL01, 311 nm, etc. ʻO "01" ke code phosphor Philips i hoʻokomo ʻia i nā helu ʻāpana ʻāpana UVB-Narrowband).

A no ka wehewehe kikoʻī hou aku:

Ka hoʻomaopopo ʻana i ka Narrowband UVB Phototherapy

Ua lilo ʻo "Narrowband" UVB (UVB-NB) i mea lapaʻau phototherapy no ka psoriasis, vitiligo, atopic dermatitis (eczema), a me nā maʻi ʻili photoresponsive ʻē aʻe. ʻO ka hoʻomaopopo ʻana i nā pono o "Narrowband" UVB me ka "Broadband" UVB phototherapy maʻamau e pono ai ka hoʻomaopopo ʻana i ka mālamalama a me nā kaʻina hana e pili ana.

Hoʻokumu ʻia ka spectrum o ka radiation optical (māmā) i nā lōʻihi nalu like ʻole o ka "mālamalama" mai 100 nanometers (nm) ma ke ʻano ultraviolet (UV) a hiki i ka 1 millimeter (mm) ma ka laulā infrared (IR). ʻIke ʻia ke kukui ʻike ʻia mai kahi o 380 nm (violet) a i 780 nm (ʻulaʻula) a ʻike ʻia ʻo "nā kala" a mākou e ʻike nei me ko mākou mau maka. ʻAʻole ʻike ʻia ka Ultraviolet a mai 380 nm a hiki i 100 nm, a ua māhele hou ʻia i UVA (315-380 nm), UVB (280-315 nm), a me UVC (100-280 nm).

ʻO nā lōʻihi nalu like ʻole o ka "māmā" e hana i nā hopena like ʻole ma nā mea. Nui nā kaʻina hana koʻikoʻi i aʻo ʻia i ka ʻepekema no ka hoʻoholo ʻana i ka hāʻawi pili o kēlā me kēia hawewe i ke kaʻina hana i aʻo ʻia. Hoʻohana ʻia nā kiʻi i kapa ʻia ʻo "action spectrum" e wehewehe i kēia mau pilina. ʻOi aku ka nui o ka "action spectrum sensitivity", ʻoi aku ka pane o ke kaʻina hana i kēlā lōʻihi nalu.

Ua aʻo ʻia ka spectrum hana no psoriasis^1,2 e hoʻoholo ai ʻo ka lōʻihi o ka nalu therapeutic he 296 a 313 nm. E like me ka mea i hoikeia ma HELU B, nā kukui UVB-Broadband maʻamau e uhi i kēia laulā a ua hoʻohana maikaʻi ʻia no nā makahiki he 60.

I ka hopena o nā makahiki 1980, ua hoʻomohala ʻo Philips Lighting of Holland i ke kukui like ʻole, i kapa ʻia ʻo "TL-01" a i ʻole "UVB Narrowband". ʻO ka ʻāpana liʻiliʻi ʻeleʻele hina i loko HELU D e hōʻike ana i nā kukui UVB-Narrowband he emi loa ka erythemogenic (ke hiki ke puhi i ka lā) ma mua o nā kukui UVB-Broadband maʻamau. ʻO ia hoʻi, hiki ke hāʻawi ʻia ka UVB therapeutic hou aku ma mua o ka hiki ʻana mai o ka erythema, a no ka mea he mea pilikia ka erythema no ka maʻi maʻi ʻili, pono e emi iki kēia mau kukui hou i ka carcinogenic no nā hopena therapeutic like.^4,5,6,7. Eia kekahi, a koʻikoʻi i ka kūleʻa i ʻike ʻia e ka home UVB-Narrowband phototherapy, ʻoi aku ka hiki ke hoʻomalu ʻia ka maʻi me ka hiki ʻole i ka paepae erythemogenic.^9,10, he pilikia mau me nā lāʻau lapaʻau UVB-Broadband. He meaʻoluʻolu ke hoʻomaopopo i ka piko o ka pale UVB-Narrowband ma kahi o ʻumi mau manawa kiʻekiʻe ma mua o ka pale UVB-Broadband, no laila ke kumu o ka inoa "Narrowband".

Ua hōʻoia ʻia nā noiʻi hou aʻe i kēia mau ʻike a ua hoʻoholo pū ʻo UVB-Narrowband i ka liʻiliʻi o nā hanana wela a me nā manawa kala ʻoi aku ma mua o UVB-Broadband. Ke hoʻohālikelike ʻia me PUVA (Psoralen + UVA-1 kukui), ʻoi aku ka liʻiliʻi o nā hopena ʻaoʻao o UVB-Narrowband a ua hoʻololi ʻia i nā hihia he nui.⁸.

ʻO kekahi hemahema o ka UVB-Narrowband ʻo ia, no ka mea, ua kaupalena ʻia ka nui o ka nui e ka hoʻomaka ʻana o ka erythema liʻiliʻi, a ʻo ka UVB-Narrowband ʻoi aku ka erythemogenic ma mua o ka UVB-Broadband, pono nā manawa mālama lōʻihi. Hiki ke uku ʻia kēia ma ka hoʻonui ʻana i ka nui o nā puʻupuʻu i loko o ka hāmeʻa^4,5,6,7. No ka laʻana, e pili ana i ka phototherapy home o Solarc ma hope o ke kūʻai aku ʻana no ka UVB-Broadband, hāʻawi ka 4-bulb 1740UVB i nā manawa mālama kūpono; ʻoiai no ka UVB-Narrowband, he koho maʻamau ka 8-bulb 1780UVB-NB. ʻO ka lākiō theoretical o ka hiki erythemogenic o UVB-Broadband i ka UVB-Narrowband aia ma ka laulā o 4:1 a 5:1.

ʻO nā maʻi ʻē aʻe e like me vitiligo, eczema, mycosis fungoides (CTCL), a me nā mea ʻē aʻe he nui i mālama maikaʻi ʻia me UVB-Narrowband, maʻamau no nā kumu like e like me ka mea i hōʻike ʻia ma luna nei no psoriasis.